Antibacterial effect and wound healing ability of silver nanoparticles green synthesized by iturin

Xixi Zhao, Liangfu Zhou, Chongyang Ai, Kai Wang, Lu Yan, Xiaoguang Xu, Chunmei Jiang, Junling Shi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In the current study, the iturin-AgNPs with 20 nm was green synthesized by the UV radiometer. The antibacterial activity of the iturin-AgNPs were evaluated in vitro and in vivo. The result showed that the iturin- AgNPs indicated a strong antibacterial activity against both gram-negative bacterium (E. coli ATCC25922 and S. typhimurium ATCC50551) and gram-positive bacterium (S. aureus ATCC29213). An in vivo model of antibacterial and wound healing on rats was developed with wound on the back. After 15 days, the control group without any treatment indicated 95% wound size while the group treated with iturin-AgNPs indicated 13% of the original wound size. This study indicated that iturin-AgNPs have high antibacterial activity in vitro and in vivo. The iturin-AgNPs are promising antibacterial agents and have potential for wounds healing.

Original languageEnglish
Title of host publication3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019
PublisherVDE Verlag GmbH
Pages530-533
Number of pages4
ISBN (Electronic)9783800750269
StatePublished - 2019
Event3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019 - Hangzhou, China
Duration: 20 Jul 201922 Jul 2019

Publication series

Name3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019

Conference

Conference3rd International Conference on Biological Information and Biomedical Engineering, BIBE 2019
Country/TerritoryChina
CityHangzhou
Period20/07/1922/07/19

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