TY - JOUR
T1 - A review of capillary pressure control valves in microfluidics
AU - Wang, Shaoxi
AU - Zhang, Xiafeng
AU - Ma, Cong
AU - Yan, Sheng
AU - Inglis, David
AU - Feng, Shilun
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/10
Y1 - 2021/10
N2 - Microfluidics offer microenvironments for reagent delivery, handling, mixing, reaction, and detection, but often demand the affiliated equipment for liquid control for these functions. As a helpful tool, the capillary pressure control valve (CPCV) has become popular to avoid using affiliated equipment. Liquid can be handled in a controlled manner by using the bubble pressure effects. In this paper, we analyze and categorize the CPCVs via three determining parameters: surface tension, contact angle, and microchannel shape. Finally, a few application scenarios and impacts of CPCV are listed, which includes how CPVC simplify automation of microfluidic networks, work with other driving modes; make extensive use of microfluidics by open channel, and sampling and delivery with controlled manners. The authors hope this review will help the development and use of the CPCV in microfluidic fields in both research and industry.
AB - Microfluidics offer microenvironments for reagent delivery, handling, mixing, reaction, and detection, but often demand the affiliated equipment for liquid control for these functions. As a helpful tool, the capillary pressure control valve (CPCV) has become popular to avoid using affiliated equipment. Liquid can be handled in a controlled manner by using the bubble pressure effects. In this paper, we analyze and categorize the CPCVs via three determining parameters: surface tension, contact angle, and microchannel shape. Finally, a few application scenarios and impacts of CPCV are listed, which includes how CPVC simplify automation of microfluidic networks, work with other driving modes; make extensive use of microfluidics by open channel, and sampling and delivery with controlled manners. The authors hope this review will help the development and use of the CPCV in microfluidic fields in both research and industry.
KW - Capillary pressure control valve (CPCV)
KW - Microfluidics
KW - Passive valve
UR - https://www.scopus.com/pages/publications/85117966834
U2 - 10.3390/bios11100405
DO - 10.3390/bios11100405
M3 - 文献综述
C2 - 34677361
AN - SCOPUS:85117966834
SN - 2079-6374
VL - 11
JO - Biosensors
JF - Biosensors
IS - 10
M1 - 405
ER -