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A novel visible detection strategy for lysozyme based on gold nanoparticles and conjugated polymer brush

  • Peng Gu
  • , Xingfen Liu
  • , Yuanyuan Tian
  • , Lei Zhang
  • , Yanqin Huang
  • , Shao Su
  • , Xiaomiao Feng
  • , Quli Fan
  • , Wei Huang
  • Nanjing University of Posts and Telecommunications
  • Nanjing Tech University

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

We developed a new strategy by combining gold nanoparticles (AuNPs) with a fluorescent conjugated polymer brush (ThNI) for colorimetric and fluorometric detection of human lysozyme. This strategy was successfully applied to assay lysozyme in buffer and human saliva. In comparison with previous reported methods, our approach has the advantages of simpleness, sensitivity, label-free property, and low cost.

Original languageEnglish
Pages (from-to)78-84
Number of pages7
JournalSensors and Actuators, B: Chemical
Volume246
DOIs
StatePublished - 2017
Externally publishedYes

Keywords

  • Biosensor
  • Conjugated polymer
  • Gold nanoparticle
  • Lysozyme

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