A mild, convenient and efficient single-step method for the synthesis of polysubstituted furans via ammonium ylide routes

Mingjin Fan, Lina Guo, Xueyuan Liu, Weimin Liu, Yongmin Liang

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

A new and convenient cyclization method for the synthesis of polysubstituted furans in a single-step via ammonium ylide routes was reported. In this process, dimethyl acetylenedicarboxylate reacted with ammonium ylide to produce polysubstituted furan in the presence of anhydrous K2CO 3 at room temperature. It is very economical, environmentally friendly and very easy to carry out.

Original languageEnglish
Pages (from-to)391-396
Number of pages6
JournalSynthesis
Issue number3
DOIs
StatePublished - 16 Feb 2005
Externally publishedYes

Keywords

  • Ammonium ylide
  • Cyclization
  • Substituted furans

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